Auto-Brewery Syndrome Advocacy and Research

This website is not intended as a substitute for medical advice from your doctor or another primary healthcare provider. If you think you have a medical condition, you should seek treatment from a licensed healthcare provider. There is no guarantee, either explicit or implicit, that information on this website is accurate or up-to-date. You must make your own decisions.

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We are here to help. Our non-profit provides advocacy, education, and research for auto-brewery syndrome also known as Gut Fermentation. Won’t you help fund this important work by donating today?

By donating to ABS research, you're making a noteworthy contribution to scientists striving for groundbreaking discoveries and potential treatments for auto-brewery syndrome. Your charitable giving could significantly influence the course of ABS research and improve the lives of patients around the world.

My Gut Makes Alcohol:

The Science and Stories of

Auto-Brewery Syndrome

This book is the first of its kind on Auto-Brewery Syndrome and provides critical understanding for patients, family members, doctors, healthcare providers, law enforcement, and the legal justice system. Dr. Cordell lived the nightmare of ABS with her husband Joe, and relates their journey and others' stories of their difficulties finding help. The science explains what we know, and what we still need to discover to identify and treat this disease.

Proceeds from the book go to fund advocacy and research for ABS.

Latest News Update

A group of researchers at the University of Aix-Marseilles in Marseilles, France may be the next heroes for people with ABS. They investigate the link between liver disease, specifically non-alcoholic steatohepatitis (NASH), and the production of endogenous ethanol in the gut by yeast and bacteria.

Babacar Mbaye and colleagues published a study in 2023 measuring several parameters including ethanol-producing microbes associated with NASH. They used high-performance liquid chromatography (HPLC) to compare fecal samples of 41 patients with NASH to the fecal samples of 41 control subjects.

The results demonstrated statistically significant elevated fecal ethanol and glucose levels in the NASH group as compared to the control group. The researchers also cultured the stool samples which grew several species of fermenting organisms. Using metagenomics they identified Limosilactobacillus fermentum, Mediterraneibacter gnavus, and Stretptococcus mutans. These data confirm previous studies that connect these organisms with NASH and other gut disorders.

The researchers conclude that a feature of NASH includes elevated ethanol and glucose in the stool of these patients. Furthermore, going forward it will be important to identify the ethanol-producing bacteria for diagnosis as well as for novel treatments. Metagenomics will be an important adjunct to cultures in identifying ethanol-producing organisms.

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This research applies to patients with Auto-Brewery Syndrome (ABS) since the hallmark of ABS is the endogenous production of ethanol. If ABS goes untreated, it can lead to non-alcoholic fatty liver disease (NAFLD) as well as NASH. We need to advocate for metagenomic testing so our providers can target treatments for the organisms. We can all advocate for change by connecting ABS to the potential for liver damage. Please help educate your providers and anyone in healthcare!

Mbaye B, Wasfy R, Borentain P, et. al. Increased fecal ethanol and enriched ethanol-producing gut bacteria Limosilactobacillus fermentum, Enterocloster bolteae, Mediterraneibacter gnavus and Streptococcus mutans in nonalcoholic steatohepatitis.

Dr. Cordell discusses the ABCs of ABS in a 4-minute video:

A Disease Should Not be a CRIME!

While suffering a flare from ABS, one of the patients in our support group was involved in a car crash with injuries to another party. The judge did not believe in ABS and the patient was convicted of a crime and served time in prison. This is a travesty of justice that must be ended through education of our legal system! Watch the video:

 

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